IMG_0259Researchers in the lab are focused on identifying lesions associated with the tumorigenesis and metastasis. The Surgical Oncology Tumor Bank has been invaluable in advancing this research possible. For example, the lab was able to help validate the role of microRNAs in a mouse model of pancreatic neuroendocrine tumors using human neuroendocrine tumor specimens. The lab is also investigating the role of Sall2 in conferring resistance to cancer therapies, how TNFR1 signaling contributes to the inflammatory response and cell apoptosis, and the role of colon cancer stem cells in perpetuating tumor growth.